Antibodies Effectively Treat Alzheimer’s-like Disease

Drs. David Holtzman and Mac Diamond of the Washington University School of Medicine recently published research in Neuron that outlined the process of studying mice for potential tau protein tangle treatment avenues. Tau is a toxic component of Alzheimer’s and other neurodegenerative diseases, due to the protein’s tendency to amass in tangles.  The aggregates, called […]

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ACE Inhibitors and Alzheimer’s Prevention

Cedars-Sinai scientists published a study in Journal of Clinical Investigation that suggests ACE inhibitors, in the right context and at the right time, can be a good thing.   Many people with high blood pressure take ACE inhibitors, medication meant to widen blood vessels by limiting activity of ACE (angiotensin-converting enzyme), a naturally occurring protein. […]

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A Vicious Cycle of Alzheimer’s and Diabetic Hypoglicemia?

A study conducted recently at the Univeraity of California- San Francisco published online in  JAMA Internal Medicine. The research was focused in on finding a close link between diabetes and dementia. According to the journal, diabetic patients with low blood sugar may have an increased risk of developing dementia, and patients with dementia or other […]

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A New Drug Reverses Lost Brain Connections in Alzheimer’s Disease

Researchers at Sanford-Burnham Medical Research Institute have developed the first experimental drug named NitroMemantine that boosts brain synapses lost to Alzheimer’s disease. The medication combines two FDA-approved drugs to stop destructive cascades within the brain, which destroys the connections between neurons and ultimatly leads to memory loss and a decline in cognition. Dr. Stuart A. […]

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Green Tea May Help Prevent Alzheimer’s Disease

Researchers at the Michigan Alzheimer’s Disease Center discovered that flavored ECGC, or epigallocatechi-3-gallate, found in green tea could bind to the toxic protein beta-amyloid and prevent its build-up. When ECGC binds to the protein, it is able to change beta-amyloid’s properties. Dr. Mi Hee Lim, lead researcher of the study, found that ECGC bonded to […]

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Alzheimer’s Disease Progression Halted Due to Increased Protein Expression

A recent report from researchers at the Massachusetts General Hospital which identifies a protein that aids the immune system in the removal of A-beta protein from the brain, could lead to new treatments of Alzheimer’s disease. According to cocorresponding author of the report, Dr. Joseph Eli Khoury of the Center for Immunology and Inflammatory Diseases […]

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A New Study Shows Small-molecule Drug through Blood-Brain Barrier

Mayo clinic researchers demonstrated within a mouse model that a synthetic peptide carrier works to deliver brain cancer chemotherapy drugs, as well as neurological medications. Neuroscientist Gobinda Sarkar, Ph.D, of the Mayo Clinic and corresponding author of the study discussed that they were able to transport eight different molecules, and much less disruptively through the […]

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Biomarker Could Aid in Revealing Alzheimer’s Early

A new study recently published in the journal Annals of Neurology discussed the identification of what could be the earliest-known biomarker that is associated with the risk of developing Alzheimer’s disease. Results of the study showed that the biomarker was present within Cerebral Spinal Fluid (CSF) for at least a decade before any signs of […]

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