Can an Epilepsy Drug Be the Answer to Preventing Alzheimer’s Dementia?

Doctor shows the patient how to use daily dose pills

An exciting research study has concluded at Johns Hopkins University and the results could be great news for the millions of patients who suffer from Alzheimer’s dementia. Epilepsy is a common neurological disorder that affects more than 50 million people in the world. A new drug, antiepileptic levetiracetam, has proved to be successful in reducing […]

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Alzheimer’s disease: Molecular Chain Reaction Found?

Researchers at Lund University in Sweden headed by Professor Singerup Linse and Erik Helistrand have recently identified a molecular mechanism behind the crucial step in Alzheimer’s that leads to the death of brain cells.   The neurological disease is associated, as a general statement, with memory loss and changes in personality.  The research at Lund […]

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Children of Long-lived Parents: Less Risk of Cancer?

  A recently completed study at the University of Exeter showed that people with long-lived parents had a twenty-four percent decreased chance of getting cancer.  The parameters of ‘long-lived’ defined as mothers who lived past ninety-one years and fathers who lived past eighty-seven years. A side study posted from the National Institute for Health and […]

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Alzheimer’s in Mice: Drug-reversible?

Within the journal Science, University of Pittsburgh Graduate School of Public Health scientists confirm that a study performed on mouse models of Alzheimer’s disease had significantly improved brain function and memory capabilities after being treated with an anti-cancer drug. The cancer drug, known as bexarotene, has previously been studied and used for the treatment cutaneous […]

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Triumphs in Genetic Sequencing of Human Diseases

  At Queen Mary University in London, researchers have conducted the largest study of genetic sequencing of human diseases known to date, identifying the genetic basis of six different diseases: autoimmune thyroid disease, celiac disease, Crohn’s disease, psoriasis, multiple sclerosis, and type 1 diabetes. According to the study, though the exact causes of these diseases […]

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Linked: Can Skin Cancer Lower Risk of Alzheimer’s disease?

A study published in the May 2013 online issue of Neurology follows researchers in Minneapolis who performed a study where 1,102 participants, of an averaged an age of 79, were followed for the span of 3.7 years and tested to see if ever they developed dementia. At the start of the study, 109 of the […]

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A Promising New Alzheimer’s Drug Stops Memory Loss

According to Northwestern Medicine Research, new experimental molecules have great promise in targeting enzymes in the brain that prevent memory loss in Alzheimer’s disease.  Developed in D. Martin Watterson’s laboratory, the molecules halted memory loss and were able to fix damaged communication between brain cells in mice. Researchers identified and targeted a key enzyme: a […]

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Antibodies Effectively Treat Alzheimer’s-like Disease

Drs. David Holtzman and Mac Diamond of the Washington University School of Medicine recently published research in Neuron that outlined the process of studying mice for potential tau protein tangle treatment avenues. Tau is a toxic component of Alzheimer’s and other neurodegenerative diseases, due to the protein’s tendency to amass in tangles.  The aggregates, called […]

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ACE Inhibitors and Alzheimer’s Prevention

Cedars-Sinai scientists published a study in Journal of Clinical Investigation that suggests ACE inhibitors, in the right context and at the right time, can be a good thing.   Many people with high blood pressure take ACE inhibitors, medication meant to widen blood vessels by limiting activity of ACE (angiotensin-converting enzyme), a naturally occurring protein. […]

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A Vicious Cycle of Alzheimer’s and Diabetic Hypoglicemia?

A study conducted recently at the Univeraity of California- San Francisco published online in  JAMA Internal Medicine. The research was focused in on finding a close link between diabetes and dementia. According to the journal, diabetic patients with low blood sugar may have an increased risk of developing dementia, and patients with dementia or other […]

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A New Drug Reverses Lost Brain Connections in Alzheimer’s Disease

Researchers at Sanford-Burnham Medical Research Institute have developed the first experimental drug named NitroMemantine that boosts brain synapses lost to Alzheimer’s disease. The medication combines two FDA-approved drugs to stop destructive cascades within the brain, which destroys the connections between neurons and ultimatly leads to memory loss and a decline in cognition. Dr. Stuart A. […]

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Green Tea May Help Prevent Alzheimer’s Disease

Researchers at the Michigan Alzheimer’s Disease Center discovered that flavored ECGC, or epigallocatechi-3-gallate, found in green tea could bind to the toxic protein beta-amyloid and prevent its build-up. When ECGC binds to the protein, it is able to change beta-amyloid’s properties. Dr. Mi Hee Lim, lead researcher of the study, found that ECGC bonded to […]

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Alzheimer’s Disease Progression Halted Due to Increased Protein Expression

A recent report from researchers at the Massachusetts General Hospital which identifies a protein that aids the immune system in the removal of A-beta protein from the brain, could lead to new treatments of Alzheimer’s disease. According to cocorresponding author of the report, Dr. Joseph Eli Khoury of the Center for Immunology and Inflammatory Diseases […]

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Stem Cells Used to Grow New Neurons, Brain Repair Circuit Identified

Researchers at Duke University have identified a new type of neuron within the adult brain capable of directing stem cells to make new neurons. The experiments are preliminary, but the hope is that the brain one day could be healing itself from within. Chay Kuo, M.D, Ph.D., an assistant professor of cell biology, neurobiology, and […]

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The Effects of Parkinson’s disease Mutations Reversed within Cells

A recent study from University of California, San Francisco scientists found that a chemical in anti-wrinkle cream could effectively prevent the death of nerve cells that had been damaged by mutations which cause an inherited form of Parkinson’s disease. According to the study’s senior scientist, UCSF chemist Kevan Shokat, PhD; the study targeted an enzyme […]

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A New Study Shows Small-molecule Drug through Blood-Brain Barrier

Mayo clinic researchers demonstrated within a mouse model that a synthetic peptide carrier works to deliver brain cancer chemotherapy drugs, as well as neurological medications. Neuroscientist Gobinda Sarkar, Ph.D, of the Mayo Clinic and corresponding author of the study discussed that they were able to transport eight different molecules, and much less disruptively through the […]

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Antidepressant May Slow Progression of Alzheimer’s Disease

According to research by the Washington University School of Medicine, published in Science Translational Medicine, a common antidepressant can reduce the production of brain plaques. Brain plaques correlate closely with memory problems and other cognitive impairments caused by Alzheimer’s disease.  Stopping plaque buildup is believed to help halt the mental decline of Alzheimer’s patients.  Scientists […]

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Amino Acids Improve Sleep in Mice with Traumatic Brain Injury

Amino Acids Improve Sleep in Mice with Traumatic Brain Injury  A study by Oregon Health and Science University, published in Science Translational Medicine, discovered a way to fix sleep disturbances in mice suffering from traumatic brain injury.  These results are important, because people commonly experience long-term and severe sleep and wakefulness issues after suffering concussions, […]

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Biomarker Could Aid in Revealing Alzheimer’s Early

A new study recently published in the journal Annals of Neurology discussed the identification of what could be the earliest-known biomarker that is associated with the risk of developing Alzheimer’s disease. Results of the study showed that the biomarker was present within Cerebral Spinal Fluid (CSF) for at least a decade before any signs of […]

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Michael Mullan: Brain Fitness Programs – a scam ?

Perform a web search on “brain scam” and you will find several articles questioning the veracity of claims made with respect to brain fitness or brain exercise programs. Are these programs a scam? One thing is clear, they appear to be rapidly increasing in popularity – all the way from self help books and DVDs […]

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Roskamp Institute in Sarasota, Florida, have shown that an anatabine compound supplied by Rock Creek has beneficial effects on memory and learning in animal models of Alzheimer’s Disease. Michael Mullan, MD, Ph.D., CEO of the Roskamp Institute and his colleague, Dr. Daniel Paris, published these findings in October, 2011 in the European Journal of Pharmacology

A study released in the January 9th issue of the Journal of Neurology suggests that nicotine patches may help individuals with early memory loss. Dr. Paul Newhouse, a professor of psychiatry at Vanderbilt University Medical Center, led a study which showed that six months of nicotine patch treatment among patients who had mild cognitive impairment […]

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Mike Mullan Alzheimer Researcher Comments on: Nicotine May Help Combat Memory Loss study by Dr. Newhouse

A recent study at Vanderbilt University Medical Center conducted by Dr. Paul Newhouse and colleagues suggests that Nicotine patches may be very beneficial in individuals with mild cognitive impairment (MCI). MCI is frequently regarded as a precursor to Alzheimer’s disease and is primarily of the type that demonstrates reduction in memory while most other functions […]

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Roskamp Institute researchers show that some antibodies but, not others may be helpful in removing the Alzheimer amyloid from the brain of Alzheimer’s sufferers.

The Roskamp Institute researchers show that some antibodies but, not others may be helpful in removing the Alzheimer amyloid from the brain of Alzheimer’s sufferers. Drs. Corbin Bachmeier, Daniel Paris, and Michael Mullan at the Roskamp Institute have been working on ways to improve the removal of the Alzheimer amyloid peptide from the brain. Using […]

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Mullan Alzheimer Research Institute Roskamp Institute aids high school students in genetic research

Dr. Mullan Alzheimer Research Institute helps high school student to be involved in research……… Roskamp Institute aids high school students in genetic research Roskamp aids high school students in genetic research By JENNIFER RICH – jrich@bradenton.com They look like scientists in their white coats, working in the Roskamp Institute’s lab using microscopes and high-tech research […]

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The Roskamp Institute investigates the role of anatabine in lowering Alzheimer’s Abeta levels.

The Roskamp Institute has had a long-term interest in finding new treatments for Alzheimer’s disease. Central to the goal of the institute is finding new ways to lower the accumulation of Alzheimers Abeta peptide in the brain. Drs. Michael Mullan and Daniel Paris and colleague investigated the role of an extract of tobacco, known as […]

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Dr. Mullan Alzheimer Presentation at Pines of Sarasota

Alzheimer’s disease: Amyloid Plaque (Excerpt from “On The Forefront”)  Video shows Dr. Michael Mullan (Dr. Mullan Alzheimer Researcher at the Roskamp Institute) presenting information to audience about Alzheimer’s Disease.Beta Amyloid Presentation By Dr. Michael Mullan (Mullan Alzheimer Researcher)

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Roskamp Institute Celebrated Veterans Day with a seminar by Alzheimer Researcher Dr. Michael Mullan

Dr. Fiona Crawford presentedVideo of Alzheimer Research Institute Headed By Dr. Mullan Presentation on Traumatic Brain Injury a synopsis of her recent study of traumatic brain injury (TBI). Her recently published findings show how TBI can affect the brain’s inflammatory mechanisms, changes in protein levels and cellular pathways, long after the original trauma. Dr. Crawford’s […]

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Alzheimer Researcher Dr. Michael Mullans Note on Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide.

A study entitled “Potent anti-angiogenic motifs within the Alzheimer’s β-amyloid peptide” was published in the January 2008 issue of the journal Amyloid. Building on previous work by Dr. Michael Mullan showing that the Alzheimer’s Aβ peptide is able to prevent blood vessel growth and inhibit tumor growth, Dr. Michael Mullan and other Roskamp Institute scientists […]

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Effect of NSAIDS on cognitive ability of Alzheimer’s Patient — Comment by Alzheimer Researcher Mullan

Medications that reduce inflammation known as non-steroidal anti-inflammatory drugs (NSAIDS) do not improve thinking abilities in normal seniors.  These findings from the Alzheimer’s Disease Anti-Inflammatory Prevention Trial (ADAPT) were published this month in Archives of Neurology. The Roskamp Institute Memory Clinic in Tampa was one of a handful of centers across the United States that […]

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Dr. Mullan’s Alzheimer Research Notes on NSAIDS and their effect on Alzheimers disease

Non-steroidal anti-inflammatory (NSAIDS) drugs such as Naproxen and Celecoxib do not improve cognition in at-risk older adults. These findings from the Alzheimer’s Disease Anti-Inflammatory Prevention Trial (ADAPT) were published this month in Archives of Neurology. The Roskamp Institute Memory Clinic in Tampa was one of a handful of centers across the United States that took […]

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