Alzheimer’s disease: Molecular Chain Reaction Found?

Researchers at Lund University in Sweden headed by Professor Singerup Linse and Erik Helistrand have recently identified a molecular mechanism behind the crucial step in Alzheimer’s that leads to the death of brain cells.   The neurological disease is associated, as a general statement, with memory loss and changes in personality.  The research at Lund […]

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Children of Long-lived Parents: Less Risk of Cancer?

  A recently completed study at the University of Exeter showed that people with long-lived parents had a twenty-four percent decreased chance of getting cancer.  The parameters of ‘long-lived’ defined as mothers who lived past ninety-one years and fathers who lived past eighty-seven years. A side study posted from the National Institute for Health and […]

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Alzheimer’s in Mice: Drug-reversible?

Within the journal Science, University of Pittsburgh Graduate School of Public Health scientists confirm that a study performed on mouse models of Alzheimer’s disease had significantly improved brain function and memory capabilities after being treated with an anti-cancer drug. The cancer drug, known as bexarotene, has previously been studied and used for the treatment cutaneous […]

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A Promising New Alzheimer’s Drug Stops Memory Loss

According to Northwestern Medicine Research, new experimental molecules have great promise in targeting enzymes in the brain that prevent memory loss in Alzheimer’s disease.  Developed in D. Martin Watterson’s laboratory, the molecules halted memory loss and were able to fix damaged communication between brain cells in mice. Researchers identified and targeted a key enzyme: a […]

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Antibodies Effectively Treat Alzheimer’s-like Disease

Drs. David Holtzman and Mac Diamond of the Washington University School of Medicine recently published research in Neuron that outlined the process of studying mice for potential tau protein tangle treatment avenues. Tau is a toxic component of Alzheimer’s and other neurodegenerative diseases, due to the protein’s tendency to amass in tangles.  The aggregates, called […]

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ACE Inhibitors and Alzheimer’s Prevention

Cedars-Sinai scientists published a study in Journal of Clinical Investigation that suggests ACE inhibitors, in the right context and at the right time, can be a good thing.   Many people with high blood pressure take ACE inhibitors, medication meant to widen blood vessels by limiting activity of ACE (angiotensin-converting enzyme), a naturally occurring protein. […]

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A Vicious Cycle of Alzheimer’s and Diabetic Hypoglicemia?

A study conducted recently at the Univeraity of California- San Francisco published online in  JAMA Internal Medicine. The research was focused in on finding a close link between diabetes and dementia. According to the journal, diabetic patients with low blood sugar may have an increased risk of developing dementia, and patients with dementia or other […]

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A New Drug Reverses Lost Brain Connections in Alzheimer’s Disease

Researchers at Sanford-Burnham Medical Research Institute have developed the first experimental drug named NitroMemantine that boosts brain synapses lost to Alzheimer’s disease. The medication combines two FDA-approved drugs to stop destructive cascades within the brain, which destroys the connections between neurons and ultimatly leads to memory loss and a decline in cognition. Dr. Stuart A. […]

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Green Tea May Help Prevent Alzheimer’s Disease

Researchers at the Michigan Alzheimer’s Disease Center discovered that flavored ECGC, or epigallocatechi-3-gallate, found in green tea could bind to the toxic protein beta-amyloid and prevent its build-up. When ECGC binds to the protein, it is able to change beta-amyloid’s properties. Dr. Mi Hee Lim, lead researcher of the study, found that ECGC bonded to […]

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Alzheimer’s Disease Progression Halted Due to Increased Protein Expression

A recent report from researchers at the Massachusetts General Hospital which identifies a protein that aids the immune system in the removal of A-beta protein from the brain, could lead to new treatments of Alzheimer’s disease. According to cocorresponding author of the report, Dr. Joseph Eli Khoury of the Center for Immunology and Inflammatory Diseases […]

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Stem Cells Used to Grow New Neurons, Brain Repair Circuit Identified

Researchers at Duke University have identified a new type of neuron within the adult brain capable of directing stem cells to make new neurons. The experiments are preliminary, but the hope is that the brain one day could be healing itself from within. Chay Kuo, M.D, Ph.D., an assistant professor of cell biology, neurobiology, and […]

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The Effects of Parkinson’s disease Mutations Reversed within Cells

A recent study from University of California, San Francisco scientists found that a chemical in anti-wrinkle cream could effectively prevent the death of nerve cells that had been damaged by mutations which cause an inherited form of Parkinson’s disease. According to the study’s senior scientist, UCSF chemist Kevan Shokat, PhD; the study targeted an enzyme […]

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A New Study Shows Small-molecule Drug through Blood-Brain Barrier

Mayo clinic researchers demonstrated within a mouse model that a synthetic peptide carrier works to deliver brain cancer chemotherapy drugs, as well as neurological medications. Neuroscientist Gobinda Sarkar, Ph.D, of the Mayo Clinic and corresponding author of the study discussed that they were able to transport eight different molecules, and much less disruptively through the […]

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Antidepressant May Slow Progression of Alzheimer’s Disease

According to research by the Washington University School of Medicine, published in Science Translational Medicine, a common antidepressant can reduce the production of brain plaques. Brain plaques correlate closely with memory problems and other cognitive impairments caused by Alzheimer’s disease.  Stopping plaque buildup is believed to help halt the mental decline of Alzheimer’s patients.  Scientists […]

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Amino Acids Improve Sleep in Mice with Traumatic Brain Injury

Amino Acids Improve Sleep in Mice with Traumatic Brain Injury  A study by Oregon Health and Science University, published in Science Translational Medicine, discovered a way to fix sleep disturbances in mice suffering from traumatic brain injury.  These results are important, because people commonly experience long-term and severe sleep and wakefulness issues after suffering concussions, […]

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Michael Mullan: Brain Fitness Programs – a scam ?

Perform a web search on “brain scam” and you will find several articles questioning the veracity of claims made with respect to brain fitness or brain exercise programs. Are these programs a scam? One thing is clear, they appear to be rapidly increasing in popularity – all the way from self help books and DVDs […]

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Dr. Mullan Alzheimer Presentation at Pines of Sarasota

Alzheimer’s disease: Amyloid Plaque (Excerpt from “On The Forefront”)  Video shows Dr. Michael Mullan (Dr. Mullan Alzheimer Researcher at the Roskamp Institute) presenting information to audience about Alzheimer’s Disease.Beta Amyloid Presentation By Dr. Michael Mullan (Mullan Alzheimer Researcher)

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Roskamp Institute Celebrated Veterans Day with a seminar by Alzheimer Researcher Dr. Michael Mullan

Dr. Fiona Crawford presentedVideo of Alzheimer Research Institute Headed By Dr. Mullan Presentation on Traumatic Brain Injury a synopsis of her recent study of traumatic brain injury (TBI). Her recently published findings show how TBI can affect the brain’s inflammatory mechanisms, changes in protein levels and cellular pathways, long after the original trauma. Dr. Crawford’s […]

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Roskamp Institute Receives Lung Cancer Research Grant

The James & Esther King Biomedical Research Program has awarded Dr. Daniel Paris of The Roskamp Institute the Small Business Technology Transfer Grant for $100,000 to conduct a research project titled: “Treatment of Lung Adenocarcinoma and Metastasis by Anti-angiogenic Fragments of Abeta.”  The Institute has previously shown that the Abeta peptite can help inhibit the […]

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Roskamp Institute Helps Florida’s Economy

FloridaTrend.com, a site covering business issues, explained in its article “SOUTHWEST: Eye Opener” on April 1st that the Roskamp Institute’s new neuroscience doctorate program is attracting researchers to Manatee County, which is suffering from layoffs in the home construction sector. These researchers and the facility’s work help bring more money to the county’s economy. Learn […]

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Roskamp Institute Supports Moves for Greater State Funding of Biotech Research

Roskamp Institute Director Dr. Michael Mullan was one of many who represented the biotech industry at the Biotechnology Legislative Caucus yesterday to request more state funding in helping the industry thrive in the state. This is important to Florida this would help the state diversify its economy more, and many organizations within the state have […]

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Nilvadipine an anti-hypertensive drug, as a potential treatment for Alzheimer’s disease

    The recent findings showing that certain anti-hypertensive (drugs which lower hypertension) drugs may be helpful in Alzheimer’s disease, is consistent with the work of the Roskamp Institute. The Roskamp Institute has been conducting pioneering research in this area for several years and is currently conducting a clinical trial in Europe to test whether a […]

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The Traumatic Brain Injury Program at the Roskamp Institute

The Traumatic Brain Injury Program at the Roskamp Institute Among the soldiers who survive conflicts in Iraq and Afghanistan, the traumatic brain injuries account for a larger proportion of their casualties than in any other US war in recent history. According to the Joint Theater Trauma Registry, established by the U.S. Army Institute of Surgical […]

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Sarasota’s Roskamp Institute Announces Participation in Multiple Sclerosis Study

We have just put out a press release announcing the Roskamp Institute’s participation in a multiple sclerosis study. Here’s a quote from Michael Mullan: “We are looking for volunteers to participate in this pharmaceutical sponsored research study to assess the effectiveness and safety of the investigational drug fingolimod, used to treat patients with relapsing-remitting MS,” […]

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Roskamp Institute recruiting for clinical trials

One of the key aspects of our research at the Roskamp Institute is clinical trials.  Without qualified volunteers, our work is impossible. We are currently recruiting volunteers for our clinical trials, which are run by our Scientific Director, Michael Mullan, MBBS, Ph.D.  We are currently recruiting for clinical trials on the following diseases. Alzheimer’s Disease […]

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Roskamp Institute Announces New Class Of Drugs That Can Impact Alzheimer’s Disease

On January 25th, we announceed the discovery of a new class of drugs that lower the production of the main pathological protein that causes Alzheimer’s diseas. Our annoucement got picked up in the press. Following is a roundup of press mentions: Sarasota’s Roskamp Institute Discovers New Class Of Drugs That Can Impact Alzheimer’s Disease Medical […]

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