Characteristics of thein VitroVasoactivity of β-Amyloid Peptides

Fiona Crawford1, Zhiming Suo, Chunhong Fang and Mike Mullan Roskamp Laboratories, Department of Psychiatry, 3515 East Fletcher Avenue, University of South Florida, Tampa, Florida, 33613 Abstract The β-amyloid (Aβ1–40) peptide has previously been shown to enhance phenylephrine contraction of aortic ringsin vitro.We have employed a novel observation, that Aβ peptides enhance endothelin-1 (ET-1) contraction, to […]

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