Reduction of b-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer’s disease

By Daniel Paris*, Nowell J Ganey, Vincent Laporte, Nikunj S Patel, David Beaulieu-Abdelahad, Corbin Bachmeier, Amelia March, Ghania Ait-Ghezala, Michael J Mullan published in Journal of Neuroinflammation 2010, 7:17 Abstract Background: Ab deposits represent a neuropathological hallmark of Alzheimer’s disease (AD). Both soluble and insoluble Ab species are considered to be responsible for initiating the […]

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Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer’s disease

Daniel Paris email, Nowell J Ganey email, Vincent Laporte email, Nikunj S Patel email, David Beaulieu-Abdelahad email, Corbin Bachmeier email, Amelia March email, Ghania Ait-Ghezala email and Michael J Mullan email The Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL 34243, USA author email corresponding author email Journal of Neuroinflammation 2010, 7:17doi:10.1186/1742-2094-7-17 Published: 8 March 2010 […]

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